The catch-22 about living (for animals anyway, the other kingdoms of life don't really have these problems as bad) is that the very processes that it takes to live are also the same processes that will kill you.
For example, one of the byproducts of cellular respiration is hydrogen peroxide. Your body is good about removing this as quickly as possible but after 60 years or so of being subjected to minute amounts of it your tissue starts to degrade causing skin wrinkles among other things.
Another example is breathing. Yes, every breath you take is literally taking you one step closer to your last. You see, oxygen is actually not good for you. It's a very potent biotoxin and was responsible for nearly killing off all life on Earth when the atmosphere suddenly become inundated with it (long story). The only reason life uses it today is because 1) life had to adapt or die to the new oxygen-rich environment which meant coming up with a way to detoxify oxygen, and 2) oxygen provides much better methods of cellular respiration. Unfortunately, each oxygen molecule also comes packaged with two free radicals (contrary to what you learned in high school chemistry, O2 is not a double bonded molecule. It is, in actuality, a single bonded molecule with a radical on each atom although it does behave like a double bonded molecule in most cases). And free radicals are extremely reactive. This results in oxygen reacting with your DNA which is a fancy way of saying it destroys it.
So unless these nanobots know how to repair damaged DNA and counteract all the suicidal crap that your body does to itself, we aren't living to 1,000 anytime soon.
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