If you take it as what it is, which is a simple shooting fan-service fest, you may have fun. Hopefully, you're a fan.
The game's story takes you through the locales of Resident Evil 0-3, excluding 2 for some retarded reason-and yes, it is a retarded reason. You play as Jill, Chris, Rebecca, the whole team, but you also get to play as Wesker, which is a change. It takes you through the different events of said games in an on-rails fashion.
The gameplay is basically the same as every other on-rails shooter. You get different guns, you shoot people. This game mixes it up to some degree by allowing knife combat and ammo scavenging, as well as finding documents that reveal more of the story. It's a good incentive to keep you attentive, if you're into that kind of thing.
If you're not, then it's no different than any other on-rails game, excluding it has the license. It can be fun fighting wave after wave of zombies if you're looking for a simple, visceral experience, but sometimes it's ridiculous, which can be blamed on the intense difficulty of the Hard setting and the easiness of the Medium setting. There's no balance. The difficulty stems from lack of checkpoints, little shooting time, and the fact that your guns barely phase a zombie. If you could see the recoil, the shooting would have been more satisfying.
As far as the presentation, it's pretty lackluster. Visuals are muddy, the VO (and dialogue) is painfully cheesy and stock, and the music is present. It shouldn't have been. Lack of music enhances the atmosphere exponentially, and the techno beats did nothing but hamper it.
Overall, it can be fun at times, especially if you have a friend, but it can get frustrating. If you're not interested in Resident Evil, then it isn't for you. If you are, then you should have some fun with the sheer feeling it gives you, but it won't last long.