A good sequel that suffers from some problems.
Fallout 2 is set long after the original. You play as a member of a tribe founded by the original character from Fallout, and not only that you are also his descendent. At the beginning of the game; after a somewhat pointless trial you learn that your tribe is screwed. Therefore the Elder sends you out into the wastes of California with nothing but your spear and the original Vault Dweller's rags to retrieve a "G.E.C.K." (Garden of Eden Creation Kit). Not unlike the original fallout; that is only the beginning.
Fallout 2 for the most part plays just like the original. You have a similar form of world map, and the same turn based combat system. If you like turn based combat in RPGs then Fallout 2 will appeal to you, but if you dislike it stay away. Fallout 2 also features the same choice based gameplay as its predecessor. You'll still make dialogue choices (occasionally humorous) that very well might effect the entire game world. Fallout 2 does go a bit overboard with the humor, however; there are occasionally bits like a "Star Trek" reference, a "Monty Python" reference and other parts that seem disjointed from the gameworld and completely unnecessary.
The graphics in Fallout 2 haven't changed from the original at all. There's also barely anything new in the graphics department except for a couple story related characters. You'll find that F2 has the same 2D sprites placed upon very familiar looking landscapes.
The audio in Fallout 2 is a mixed bag like its predecessor. The voice acting and sound effects are all well and good, but the music is practically non-existant and what is there is so silent and so forgettable that it won't really matter.
Fallout 2 is a goodfollow up to the original game overall, but is flawed by some unnecessary bits of humor and the "same old, same old" that makes Fallout 2 often feel like a retread of the original. If you're a fan of the first try it; if you haven't played the first yet you're better off playing that one before this one.