Wow i can'y believe noones thought about ratchet and clank here ._. anyway I'm going to have to say:

1, R.Y.N.O., all 4 of them they were all great. (Ratchet and Clank)

2, Seraphim Experimental Nuke Launcher, no nuke has ever been so devestatingly beautiful. (Supreme Commander)

3, The Hunter Olympus, in the correct hands its a weapon of mass destruction. (Burnout Paradise)

4, Skorms Bow, add a full level multi shot and it spells doom. (Fable)

5, Lambert carbine, no words can describe its beauty. (Battlefield 2142)

Annnd thats all for now folks bye.