You guys should have mentioned Dead Space. From the intro to the game, you are made aware of Isaac's love interest, Nicole, and the game is also about trying to find her as well as fix the USG Ishimura. After a few haunting encounters, the truth is laid out that the Nicole you found was only a figment of your imagination, and the actual Nicole killed herself at the outset of the Necromorph outbreak. This is made clear by the Easter Egg using the first letter of each chapter in the game, spelling out, N-I-C-O-L-E-I-S-D-E-A-D. And who can forget her attacking you in Necromoprh form at the game's conclusion! Heartbreaking!
The Condemned series really messed with my head, not knowing if things I'm seeing out of the corner of my eye are real or hallucinations. Hovering shadows shaped like people trying to attack me in an abandoned library really get to me. Or things moving without anyone around to move them. Eghhh... I'm getting creeped out just thinking about it. And on the same note, I saw someone mention Clock Tower! I totally forgot about that old PlayStation gem until someone recommended it here! Good game. Parasite eve was also creepy, but wouldn't necessarily fit on here.
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