No, because if you beat the game...SPOILER.............................................................................................................................................................................................................................................................................................................................................................................. .......................................................................................................................... .......................................................................................................................... .......................................................................................................................... .......................................................................................................................... .......................................................................................................................... .......................................................................................................................... .......................................................................................................................... .......................................................................................................................... you'll know that Desmond is dead so it wouldn't make sense to be able to use him anymore.
Knightfall already happened in the Arkham Universe. In Arkham Asylum, if you lose during the Bane fight, Bane then references his breaking Batmans back in the past.
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