I haven't gotten 100% on any PS3 game. It would probably make gaming feel like a chore for me rather than a fun experience. At some point I'll probably get 100% in LBP, Valkyria Chronicles, Uncharted, and Lair, mostly because I enjoy those games so much and they don't require as much investment as games like Oblivion. MGS4 is great but I can't see myself ever getting the big boss medal, my hat goes off to those that do.

EDIT: I want to try and get 100% completion in SSDHD. I think the trophies in that game are fun challenges.

paperdollparade

Most of the trophies weren't a chore. The games were all fairly easy (Except for Crushing mode in Uncharted which made me RAGE) so doing the trophies, more often than not, made the games more fun by adding longevity and extra challenges. The only chore trophies I have come across which will take me ages are the Wanted, Flying the Co-op and AWP trophies on GTA 4. Mainly because I have to; a) find a couple of decent players to help me with the Flying the Co-op trophy and b) spend 30-40 hours levelling up to 10 to get the wanted trophy.