The Obvious answer seems to be Starcraft, which I completely agree with.  I'd love a massive 2d Chronotrigger remake/sequel, no unneccesary graphical updates, make it look nice and feel like to old one, maybe.  A new Diablo would be good.  Fallout, King's Quest, The Dune ADVENTURE game, not the sequel that ended up being the first RTS, and Rock and Roll Racing would be awesome.  I'd like a remake of Ultima 7 too.  The full version, wich ended up being something like 3 games long, maybe 4, I forget now.  And a remake of the Xeen games, in the Might and Magic series, would be insanely cool.  Final fantasy 6 (3 in US) remake would be superb, as well.  There's to many games!