Still Can't Get It Right
The weapon making is sort of new just find items and if you've got the right ones you can make that new weapon. Obviously the ultimate weapons probably need a lot of rare items to build but that's never new is it. The familiar system is back as with S.O.T.N you get strange creatures, which help, fight off those zombies and devils.
All in all this game is worth playing for at least 1 completion then maybe you may stop for a while. And pick up where you left providing that there isn't a game out there that's worth swapping it in for.