I use Vista and if you have a good system with lots of RAM, I highly recommend it. I do notice the difference between windows XP and vista in game, don't judge the differences by photos because you'll think there is hardly any difference.
I run on very high settings 1400x900 with x2AA and the game is immaculate. Granted I had to build a new system in order to achieve those settings but it was well worth it.
Plus, Vista SP1 will be released soon which has gotten great reviews in the beta stages, it fixes numerous problems and increases speed! Good luck.
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