In a perspective of story, i mean. Not necesarily gameplay. 

I know it's hard to think in a ME game without having The Reapers as the main enemies, but still is fun just to iagine the possibilities.

For example:

- If Wrex is alive and you cured the genophage, you meet a Krogan named Mordin.

- The quarians life with their alternative versions of theis suits, but without their helmets.

- If Wreav was the Krogan leader, a future war with the Salarians and Turians eventually breaks. 

- What would happen to the other squadmates and what would change if you romanced them?

Tali:

Miranda:

Jack:

Samara:

Ashley (if survived)

Garrus:

Liara:

Grunt:

Jacob:

Vega:

Kaidan:

Javik:

Try it for fun :)

Speaking of DLC characters, when are those going to avaible? 

Oh, and answering to the topic, i would have also liked to see Anna and Eddie from Tekken and Alex and Blair Dame (from Street fighter EX... i know all the legal issues but still, great character).