While still an awesome game in an awesome series, New Blood could stand for some new innovations.
The problematic familiar aspects to the game are that a lot of the surgeries are very similar to the previous game. I'm pretty sure that the first putting the bones back together was exactly from the surgery like that in Second Opinion. Also, there are no new tools to use on your surgeries. There are a few new mechanics during special situations, but your core tools stay the same. It's safe to say that the surgeries and tools could be varied up a little bit.
Moving on past the bad, the good is what fans of the series love. First of all, it's challenging. There are multiple difficulty levels, but even on normal towards the end of the game, you'll be stressing.
The visuals are as ever highly stylized. Not so much the surgeries themselves, but in between. The character models once again are anime esque, but are quite possibly better looking than the original.
Going along with the presentation, the sound quality in the game has been improved greatly. It has a great soundtrack and VOICE ACTING! Thank god for that, because if you know Trauma Center, you know it's a dramatic, wordy game and reading everything gets to be a chore. Voice acting in this series is a godsend, and the good thing is, none of the voices are particularly bad.
A new edition to the series is co-op mode. This makes things easier in a sense, but at the same time if you're not in sync with your buddy, well things can get to be a mess and then your patient just gets on the four o'clock train to six feet under FAST.
Over all, Trauma Center is a great sequel, it just could stand to see some new variations to the series. If you're a fan of the series, buy it, if not, its a great time to become one.