As a native Californian, I actually have a bit of an affection for earthquakes. They scare the non-natives something fierce, and it's a really dramatic way for nature to let you know your place. Mostly, though, they're like a fun, unpredictable ride--you usually only notice after stuff has already started shaking, and then you get that great nervous tension of wondering if it's going to keep going, if this is going to be The Big One. When it's over, you rush to the US Geographical Survey site to see the magnitude and epicenter of the quake. It's just an occasional part of life, like hurricane cellars in the south.
That said, San Francisco has not seen an earthquake the magnitude of the 1906 quake since. Loma Prieta was close, but as you move up the Richter scale, each point of magnitude represents an exponential increase in severity. So, a 7.8 might not seem that much more severe than a 6.9, but they're worlds apart.
Granted, the 1906 quake was such a disaster due mostly to fire, but the World Series is partially credited for preventing the Loma Prieta quake from being as terrible as it could've been, since more people throughout the Bay Area were at home or in bars watching the Giants lose miserably to the A's, instead of dying under collapsing freeways. The Bay Area is a much more densely populated region now than it was even in 1989, and I can't help but wonder what sort of chaos would ensue if such a quake hit today.
What does this have to do with video games? Only that reviewing Disaster Report hasn't prepared me for the real thing in the slightest bit.