I have the Switch and the Xbox controller for the PC. One thing that's really annoying is that when using the Switch Pro controller even though it has the same layout as the Xbox controller the "ok" button is bottom left on the Switch and bottom right on the Xbox. Cancel is bottom right on the Switch and bottom left on the Xbox. Not only that, but the layout for the Xbox is "x y" on top, "a b" on the bottom, which makes sense since it's in alphabetical order. On the Switch it goes "y x" on top, then "b a" on the bottom.
So when I go back and forth I end up making mistakes with "ok" and "cancel" just navigating through menus.
Also, I've been playing Dragonball FighterZ on the Switch and Injustice 2 on the PC. They have the same light and medium attack layout, but the special button is reversed. This just makes muscle memory very hard and is very confusing! Was this done on purpose?