Played the game with the following spec:
i7 2600k, 256gb ssd, 4gb ram, AMD 6870, 3x23" Monitors in 5760x1080 (Eyefinity) in ultra high.
First of all, this game seems to be superbly optimized, it's been a few years since I last upgraded my PC, however I was able to run in ultra and eyefinity without a hitch.
I decided to play after finally finishing Fallout New Vegas, after a lot of reading, it sound a great title, so I decided to get it, and what a great decision it was.
The game has a very dark setting, engaging gameplay and a very interesting story, I don't know if it was because I was so engaged, but the game seemed to fly by, and just when you think it is ending, there are some turn around of events and the game continues.
Overall I was left feeling incredibly satisfied after playing and even did some replaying, and there is not much else I can ask for.