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Carlos Santana strumming in Guitar Hero 5

In April 2008, Carlos Santana sounded like he didn't want anything to do with Guitar Hero. Speaking with the Orlando Sentinel, the famed guitarist said, "If you're going to spend that much time and energy, get yourself a real guitar… I'm not into virtual anything, if it's not the real thing,...

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In April 2008, Carlos Santana sounded like he didn't want anything to do with Guitar Hero. Speaking with the Orlando Sentinel, the famed guitarist said, "If you're going to spend that much time and energy, get yourself a real guitar… I'm not into virtual anything, if it's not the real thing, man."

No Caption Provided It seems he had a change of heart, however, as the famed guitarist will now appear as a playable character in the upcoming Guitar Hero 5, with a live recording of his acclaimed song "No One to Depend On." Activision also announced today that Santana will only be one several new playable musicians in this installment of the $2 billion-grossing rhythm-based series.

"His accomplished career and breadth of musical style are a great illustration of the variety of rock experiences we have included in the game, and we are excited to announce him as the first of five playable in-game artists," said vice president of music affairs for Guitar Hero Tim Riley, conveniently overlooking Santana's earlier comments.

For a man who has produced over 40 albums and won 11 Grammy Awards, Santana rarely shows up the Guitar Hero series' set list. Currently, he has one song in the series, a cover of "Black Magic Woman" in Guitar Hero 3: Legends of Rock and Guitar Hero: On Tour.

Earlier this month, Activision partially revealed the set list for Guitar Hero 5, which will include such artists as The White Stripes, Tom Petty, Bob Dylan, Kings of Leon, and Vampire Weekend. It ships September 1 in the US and will be available on the Xbox 360, Nintendo Wii, PlayStation 3, and PlayStation 2. For more information, check out GameSpot's previous coverage of Guitar Hero 5.

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