Prototype wins the better story battle vs. inFamous, but maddening controls make it lose the better game contest.
Prototype is littered with annoyances like a gnat that endlessly circles your head, never going away. The Manhattan map is far too big to not have some auto-travel mechanism, though at least even if you've never been to NYC, if you played GTA IV you can navigate with ease.
While combat is very fun, there are almost too many moves, and many will fall by the wayside as you pick two or three as your bread-and-butter. The Devastators you get access to are visual impressive and imposing. You are able to pick up military weapons, which can be mildly fun, but tossing cars at enemies never stops being a thrill.
The parkour aspect is fun, but all too often you don't 'get' to use parkour, but are 'stuck using' parkour'; namely, in timed events where you need to melee tanks you're forever accidentally jumping atop them or kicking yourself away, losing precious seconds of time. (for events like those, a 'turn off parkour' toggle would've been a godsend) The imprecision of the parkour also hurts in checkpoint race events and against some larger creatures in confined spaces.
There's also landmark orbs and hint globes to collect, but what qualifies as a landmark in most cases should be designated 'random hidden orb', while the hints are often things a small child would have figured on their own even if the game hadn't already specifically told you the technique several hours ago.
The achievements are a little poor, with the same 10 GS assigned to many tasks despite widely different difficulties in attaining them, while another offered for completing several missons without a military alert would be more palatable if at least half the missions didn't have scripted alerts.
It was a fun game overall, and I still recommend it at the less than $20 pre-owned it can be found for, but needed a tad more polish.