I saw this on the internet, and did literally laugh out loud--Mario takes a trip to Vice City, pimps his ride and rescues a 'princess' on a street corner.
(I guess viewer discretion advised, probably not suitable for under 18s) Take a look...
I loved the ending, "Hmm... Raccoon City, that sounds lovely..."
For anyone that doesn't know, Robot Chicken is a popular stop motion animated television series created by Seth Green and Matthew Senreich, and is shown as part of the 'adult swim' programming of the Cartoon Network in the US, and on Bravo in the UK. It's one of the only American comedy shows I actually like, being a Brit.
Robot Chicken has previously shown other video game funnies--in one the Halo crew tackled the Donkey Kong game, by infiltrating the map and setting a timed bomb to blow up under the gorilla. In another, the Final Fantasy VII crew were tasked with working in a fast food restaurant, and villain Sephiroth attacked Cloud with his special 'unpaid overtime' move. You can probably dig those out on youtube, too.
The episode that shows the Mario clip is episode 39, was first aired on November 5 and is called 'Lust For Puppets', if you wanted to see the original.