San Andreas is by far the best GTA game in the GTA series.
A major difference in this GTA game from others is that the game does a better job at telling you what you need to do for missions, as in past GTA games, the text would just say "go kill this guy" but in San Andreas it more says "go to such and such place and kill this person" which is a much better explanation.
The gameplay is no different either, the gameplay is what you would expect from a GTA game and even if you don't do the missions there is plenty more to do around the state.
The character moddles n this game are also well disigned although you would find that the characters in the cut sceens have pixulated body parts ect, which made it look kind of weird.
The graphics department could of been a bit better with frame rate but being such a big game it still looks great.
Overall, this game is a game worth getting.