| Name | Location | Significance |
| Ian | Ebonheart Archer and Protector of Fighters Guild (wandering NPC) | |
| Ibanammu Assutladainab | Ashlander Camp Wise Woman (just south of Molag Mar) | |
| Ibarnadad Assirnarari | Suran (Apothecary) | Barters extensive selection of potions and reagents. |
| Ibasour Sershurrapal | Ashlander Camper (SE of Erbenimsun Camp) | Hostile NPC |
| Idhassi | Rotheran Prisoner (Arena) | Slave |
| Idhdean Tailas | Arkngthand denizen | Hostile NPC |
| Idlami | Yansirramus Barbarian (outside shrine) | |
| Idonea Munia | Vivec Foreign Quarter healer (Upper Waistworks) | Spells. Barters some basic potions. |
| Idrenie Nerothan | Cavern of Incarnate Failed Incarnate | Gives Master's Lockpick and Probe. |
| Idronea Sadri | Assarnud denizen | Hostile NPC |
| Idros Givyn | Ald'ruhn Crusader (Venim Manor Private Quarters) | |
| Idroso Vendu | Vivec Telvanni Quarter Mage and Oathman of Great House Telvanni (Temporary Housing) | Target of a Morag Tong quest. |
| Idula Moren | Kumarahaz denizen | Hostile NPC |
| Ienas Nadus | Bal Isra Redoran Stronghold guard | |
| Ienas Sarandas | Ald'ruhn resident (residence) | Ienas is the target of several minor quests in Ald'ruhn. |
| Ienase Radas | Vos Commoner (wandering NPC) | |
| Ienase Relnim | Vivec St. Olms Quarter Plaza Noble (Upper North-Two) | |
| Ienaso Adren | Ebernanit Shrine denizen | Hostile NPC |
| Igna | Druscashti Quarra Clan Vampire (Lower Level) | |
| Iingail | Shishara denizen | Hostile NPC |
| Iirenoore | Yesamsi denizen | Hostile NPC |
| Ilasour Tansumiran | Gnisis Egg Miner (cave residence) | Plays a role in a Hlaalu quest to develop a stronghold. |
| Ilden Mirel | Vivic Temple Quarter Thief (Holding Cell) | |
| Ildogesto | Galom Daeus Vampire | Berne Clan Vampire |
| Ildos Rothren | Andasreth Fort denizen | Hostile NPC. Trainer. |
| Ilen Faveran | Balmora Temple Initiate and Enchanter (Temple) | Enchants. Barters magic shields and many scrolls. |
| Ilet Tistar | Vivec Temple Quarter (Hall of Processing) | |
| Ilfhild | Battlemage on Ship Grytewake, South of Hla Oad | |
| Ilmeni Dren | Vivic St Delyn (Canal Canal South-one) | Gives quests for Great House Hlaalu. Target of a Thieves Guild quest given by Gentleman Jim Stacey in Vivec Foreign Quarter |
| Ilmiril | Ald'ruhn Acrobat (residence) | |
| Ilmyna Romoren | Milk denizen | Hostile NPC, equipped with Dreugh armor. |
| Ilver Aralas | Saturan denizen | Hostile NPC |
| Imare | Balmora Nightblade of House Hlaalu (Hlaalu Council Manor) | Spells |
| Iminda | Ashmelech Pilgrim | |
| Im-Kilaya | Ebonheart Agent and Twin Lamps of the Twin Lamps (Argonian Mission) | Plays a role in quest given by Relam Arinth in Hla Oad. |
| Imsin the Dreamer | Fort Buckmoth Master-at-Arms and Knight Protector of the Imperial Legion | Trainer. Gives quests for the Imperial Legion. |
| Ince | Sadrith Mora Slave (Gateway Inn South Wing) | |
| Indrel | Shishi Cave Denizen | Dead NPC |
| Indrele Rathryon | Seyda Neen Commoner (wandering NPC) | Target of a Thieves Guild quest given by Gentleman Jim Stacey in the Vivec Foreign Quarter. |
| Iner Ralderan | Ebernanit Shrine denizen (outside shrine) | |
| Inera Faryon | Vivec St. Olms Canal Commoner (North-Two) | |
| Inerri | Vivec Telvanni Quarter Slave (Cantoon, behind locked door) | |
| Inganar | Ularradallaku Shrine denizen | Hostile NPC, who has one of the Sanguine items, the Glove of Sanguine Safekeeping. |
| Ingokning | Ebonheart Assassin (Skyrim Mission) | |
| Iniel | Wolverine Hall Guildguide of the Mages Guild (Mages Guild) | Travel. Plays a role in an Aundae clan vampire quest. |
| Inorra | Caldera Mine slave (Caldera Mine) | |
| Irarak | Ginith Ancestral Tomb Vampire | Target of a vampire quest given by the Quarra clan. |
| Iratian Albarnian | Caldera Master-at-arms and Trooper of the Imperial Legion (Shenk's Shovel) | Trainer |
| Irbran Kirbatha | Arkngthand denizen | Hostile NPC |
| Irer Nervion | Falasmaryon dead body | Dead NPC, who plays a role in a quest given by Faral Retheran in Vivec Redoran quarter. Equipped with glass armor. |
| Irgola | Caldera Pawnbroker (Pawnbroker's shop) | Barters a variety of weapons, armor, magic and miscellaneous items. |
| Irinwe | Addadshashanammu Shrine denizen | Hostile NPC |
| Irna Maryon | Tel Aruhn Apothecary and Oathman of Great House Telvanni (Tower Living Quarters) | Barters a wide range of potions, including Rising Force potions, and reagents |
| Iroroon | Ashmelech Vampire | Aundae clan vampire |
| Irvama Othrelas | Vivec farmer (outside the city, near the Gro-Bagrat Plantation) | |
| Irver Fevur | Ald'ruhn Commoner (Venim Manor Entrance) | |
| Irvsie Othran | Rotheran Denizen (Arena) | Hostile NPC. Has the Rotheran slave key. |
| Irwaen | Tel Branora Sharpshooter and Hireling of Great House Telvanni (on hill west of town) | Target of a quest given by Mollimo of Cloudrest in Tel Branora |
| Itan | Balmora Commoner (residence) | |
| Itar the Gentle | Dagon Fel Commoner (wandering NPC) | |
| Itermerel | Balmora Mage (Eight Plates) | Target of a quest given by Ranis Athrys in Balmora, Itermerel only arrives in town just prior to the quest. |
| Iulus Truptor | Ebonheart, Imperial Chapels | Trainer, barters some guides. Gives quest for the Imperial Cult. |
| Ivela Uvenim | Milk denizen | Hostile NPC |
| Iveri Llothri | Witch in wilderness just west of Indoranyon Fort, by a campfire | The target of a quest given by the barbarian nearby, |
| Ivramic Sarandas | Sadrith Mora Mage Nightblade (Tel Naga Upper Tower) | |
| Ivrosa Verethi | Dren Plantation Thief (residence) | Trainer |
