| Name | Location | Significance |
| Caccian Hers | Nund denizen | Hostile NPC |
| Caius Cosades | Balmora Blades Guildmaster (residence) | Trainer. Gives quests on behalf of the Blades, the game's main quest. |
| Calmanide | Assumanu Sorcerer | Hostile NPC |
| Calvario | Nerano Ancestral Tomb Vampire | Plays a role in a Blades quest initiated by Nibani Raesa in Urshilaku Camp. |
| Camandil | Falensarano denizen (lower level) | Hostile NPC |
| Camas | Almurbalarammi Shrine denizen | Hostile NPC |
| Caminda | Suran Acrobat (House of Earthly Delights) | |
| Canctunian Ponius | Ebonheart Factor-in-Chief of the Ebonheart Agency of the East Empire Company (East Empire Company Hall) | Target of quests given by Iulus Truptor (Imperial Cult) in Ebonheart and by Nileno Dorvayn in Balmora (Great House Hlaalu). |
| Candodia Felannus | Caldera Commoner (residence) | |
| Cania Mico | Tel Vos Warrior and Hireling of Great House Telvanni (Barracks) | |
| Carecalmo | Ashalmimilkala Shrine denizen | Hostile NPC. Target of an Imperial Cult quest given by Lalatia Verian in Ebonheart and the target of a Morag Tong special duties quest. Wears a Sanguine item needed by the Morag Tong. |
| Caryarel | Gnaar Mok Commoner (wandering NPC) | He plays a role in an Imperial Cult quest initiated by Kaye in Ebonheart. |
| Cassius Olcinius | Vivec St. Delyn Plaza Invisible Man (wandering NPC) | Gives a quest. |
| Cavortius Albuttian | Ebonheart Warrior and Champion of Imperial Legion (Imperial Guard Garrison) | |
| Celegil | Shishi Ruins denizen | Dead NPC |
| Celegorn | Sadrith Mora Thief (Dirty Muriel's Cornerclub) | Trainer |
| Celria | Tel Mora Spellsword (Elegnan's Clothier shop) | |
| Chalone | Vivec Foreign Quarter Plaza Commoner (wandering NPC) | |
| Chalureel | Zebabi denizen | Slave |
| Chanil-Lee | Ebonheart Sorcerer and Journeyman of the Mages Guild (Six Fishes) | Trainer |
| Chaplain Ogrul | Gnisis Healer and Acolyte of the Imperial Legion (Fort Darius) | Spells. Barters some potions and reagents. |
| Chark | Esutanamus Shrine denizen | Hostile NPC |
| Cheesh-Meeus | Hinnabi denizen | Slave |
| Chirranirr | Balmora Thief (South Wall Cornerclub) | Trainer. Barters some tools. |
| Chiwish | Rotheran Prisoner (Arena) | Slave |
| Chrelm | Minabi denizen | Hostile NPC, who has the Minabi slave key. |
| Chuna | Balmora Bard (Lucky Lockup) | |
| Cidius Caro | Tel Vos Battlemage and Retainer of Great House Telvanni (Barracks) | |
| Ciel Nestal | Vivec Telvanni Quarter Spellsword and Retainer of Great House Telvanni (Tower) | |
| Cienne Sintieve | Ald'ruhn Alchemist (Alchemist shop) | Barters potions, reagents and alchemy tools. |
| Cinda | Ashir-Dan denizen | Hostile NPC |
| Ciralinde | Tel Aruhn Underground Slave | |
| Cirges Adrard | Vivec Telvanni Quarter Archer and Retainer of Great House Telvanni (Tower) | |
| Cirwedh | Vivec Telvanni Quarter Scout and Retainer of Great House Telvanni (Tower) | Trainer |
| Clagius Clanler | Balmora Outfitter (Clagius's shop) | Barters some miscellaneous items |
| Clasomo | Galom Daeus Vampire | Berne Clan Vampire |
| Clecentor Aerius | Pinsun denizen | Hostile NPC |
| Clendil | Ald Daedroth denizen (Left Wing) | Hostile NPC |
| Clibergus Urgelian | Sadrith Mora Trader (Gateway Inn) | |
| Clilias Pullia | Gnisis Guard and Recruit of Imperial Legion (Madach Tradehouse) | |
| Cluson | Pinsun denizen | Hostile NPC |
| Cocistian Quaspus | Buckmoth Fort Apothecary and Initiate of the Imperial Cult | Barters a wide range of potions, reagents and alchemy tools. |
| Codus Callonus | Ald'ruhn bookseller (bookshop) | Barters books. |
| Coirtene Liore | Arkngthand denizen | Hostile NPC |
| Conoon Chodala | Cavern of Incarnate Failed Incarnate | Gives an Axe and Boots. |
| Cractia Jullalian | Vivec Foreign Quarter Plaza Alchemist and Apprentice of the Mages Guild (Mages Guild) | Barters large variety of potions, reagents and alchemy tools. |
| Crassius Curio | Vivec Hlaalu Quarter Agent and House Cousin of Great House Redoran (Curio Manor) | Trainer. House Hlaalu sponsor, and gives quests for House Hlaalu. His support is required in order to be appointed Hlaalu Hortator. |
| Crazy Batou | Maren Ancestral Tomb denizen | Hostile NPC, although if you kill him, you'll receive a message stating you've broken the main quest. |
| Crazy-Legs Arantamo | Vivec Foreign Quarter Thief (Canalworks bookseller's shop) | Trainer. Barters a few books and guides. Can remove bounties. He also will tell you the location of one Propylon Index. |
| Creeper | Caldera Skamp merchant (Ghorak's Manor) | Barters items (other than reagents, non-magical clothing and jewelry) and pays full price, and has 5,000 gold every 24 hours. The best merchant in the game. Also buys "illegal" items, such as Skooma. |
| Cristus Lyne | Arkngthand denizen | Hostile NPC |
| Crottus Cedus | Shurinbaal denizen | Hostile NPC |
| Crulius Pontanian | Fort Moonmoth Enchanter and acolyte of the Imperial Cult | Barter a few magic weapons, scrolls and items |
| Culumaire | Balmora commoner (Lucky Lockup) | |
| Cumanya | Dubdilla denizen | |
| Cun | Tel Branora Sharpshooter and Retainer of Great House Telvanni (on hill west of town) | Target of a quest given by Mollimo of Cloudrest in Tel Branora. |
| Cunius Pelelius | Caldera Agent and Lawman of the Great House Hlaalu (Governor's Hall) | Trainer. Target of an Imperial Cult quest from Iulus Truptor of Ebonheart, and plays a role in a Redoran quest initiated by Garisa Llethri in Ald'ruhn. |
| Cuunel | Sulipund Cave Monk and Hireling of Great House Telvanni | |
