Sim City 5 Regions?.

In sim city 5 regions can you have one region as industry and another housing and another commercial or have they got to have all of them in the same region?. Thanks.

Build what you want and where you want

By region, you do just mean each city right? Not the different maps? If you mean each city, you can, but I don't believe they will be very big or profitable. I can't say for sure though. It has changed a lot since I was actively playing.