- Mulcahy stated that several new creatures will appear. Only the Crows and a new breed of "Super Zombies"(most likely a Crimson Head, as referred to in the games) have been confirmed to appear so far. Hunters have been rumored to appear in it as well.
- Like Resident Evil 5 (the game), Extinction takes place in a dry, harsh, desert wilderness. This is a huge departure from the usual dark and drab locations of most zombie films and games. Similar to From Dusk Till Dawn.
- Alice returns to the mansion featured in the first film, or a replica (direct reference to Code: Veronica), possibly Spencer mansion.
- At the end of the movie Alice fights the Tyrant in the Spencer Mansion much like Jill Valentine or Chris Redfield do in the original Resident Evil.
As a reference to the original Resident Evil Captian Alexander Slater gets killed by the Tyrant much like Albert Wesker does in the original
The Tyrant in this movie has a resemblance T-002 Tyrant from Resident Evil but attacks like the T-091 Tyrant does with his tenticles (from Resident Evil:Dead Aim)
http://en.wikipedia.org/wiki/Resident_Evil:_Extinction
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