At the start of the chapter, head to the maintenance shaft to reach a room with a Bench Station. Here, you can upgrade your weapons, rig and stasis with any spare nodes you might have collect. You can also purchase nodes at a store, though that might be economical unsound so early in the game.
You'll come across a locked door that will require a node to unlock. Thankfully, you'll soon also come to a spare Power Node lying around. Use the node on the door to find a stash filled with ammo and sellable items. Watch out though, as a Necromorph might sneak from behind as you collect your goods.
Check around for some extra cash and proceed to the laundry room. You'll get swarmed by a huge wave of Necromorphs. Both stasis and kinesis will be key in saving on ammo and taking down these continual threats.
In the next room you'll come across Exploders that carry large explosive sacks. They can do heavy damage if you're in the blast radius. However, the sack is also their weak point. Shoot at it to kill off not only the Exploder, but any other Necromorphs around it.
You'll next arrive at the train tracks and a number of corpses around the room. To prep for the battle and make things easier you should actually use kinesis to pick up the bodies and toss them on to the tracks. An Infector will soon appear that will attempt to revive any of the corpses left. However, if you dumped the bodies, it will have nothing to bring to life. Stasis the Necromorph and kill it quickly with your cutter.
Enter the train and you'll need to take down more Necromorphs. The train is narrow, so there is no real room to avoid their attacks. Kill before you take damage is the best strategy. The train will start to break apart and collapse. Avoid any enemies and dash to the other end of the train.
The train will crash, but will keep you trapped upside down, hanging from the exit. You can't move to avoid the next wave of enemies, but can shoot them down and use kinesis to acquire more ammo. Your prime targets should be the Exploders, followed by Pukers and Slashers. After the smaller enemies are dealt with, a Tormentor will appear from the train. Shoot its glowing yellow sacks to take it down and complete the chapter.