Great, but buggy.
The Mohave desert and Vegas environment, questing, character and weapon diversity, factions, and other aspects of the game
make it very enjoyable. It's one of those titles that you'll find hard to put down once you pick it up.
With that said, the studio should have taken more time to properly test the PC version as it clearly was rushed to release. There are a fair number of bugs that clearly indicate it was not tested thoroughly. I expect we'll see a patch in the near future to iron out inventory problems and the like.
Regardless of the technical issues, the game is still very playable. If you're a Fallout fan or for that matter an RPG fan, this is a title you shouldn't miss.