Great story, gameplay mechanics and multiple endings make this new entry in the Deus Ex series a must play.
I won't spoil much of the story, because the story, and how you play through Human revolutions is its selling point. You have to choose adam's augmentations, and by choosing the right ones they can either help you pass certain scenarios, or would make you wish you had chosen something else.
Speaking of augmentations, I especially like the ability to 'persuade' certain characters in the game's speech challenges to turn their rhetoric against them, and thus win the challenge (and gain a trophy too).
Since this is the PS3 version, there are a a ton of trophies and sidequests that you can miss on your first play through; unless you use guide. You could potentially platinum the game in one play through, although that would take out much of the fun in the game.
Overall, a great game for both RPG and Deus Ex fans alike.