Totally different than PC, but not as bad, but still....
First off, I would get the game with a manual. Unfortunately, since its only available used it'll be harder to get.
The NUMBER ONE MAJOR DIFFERENCE is that this game isn't in real time. You can only move/create one unit each turn/day, and even then they have limited walking space. This is a good idea for battle, but villagers, monks, and creation, its a bit time consuming.
Next is resources. Wood and stone don't exist. Also you don't mine/collect* here. You build a mill/camp on a gold rock/wheat and then for mills build a farm, and start earning income each day. (*There are some bonuses that you do get though)
Several units don't exist especially since there's only 5 campaigns. Like the gun powder men, they don't exist. Also towers are for healing/defense only. The wall also doesn't exist. Monks can heal, collect relics, and convert units but not buildings.
And also the cheat codes don't work (like MARCO, POLO, ROCK ON, ROBIN HOOD).
In addition there are pre-set skirmish maps, but you can't make your own map.
The music is different too, except on the title screen.
Lastly, the game can only save one file, which kinda sucks if your working on multiple campaigns or if you made a mistake on one (but I guess one is better than none).
But overall, the game isn't that bad and has a lot of playtime (you could be looking at a whole summer evenings even).
But I'd rent it first or get it at a low price.